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National Institute on Drug Abuse
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Q: What are the long-term effects of marijuana use?
A: Findings so far show that regular use of marijuana or THC may play a role in some kinds of cancer and in problems with the respiratory, immune, and reproductive systems.
- Cancer
It's hard to know for sure whether regular marijuana use causes cancer. But it is known that marijuana smoke contains some of the same, and sometimes even more, of the cancer-causing chemicals as tobacco smoke. Studies show that someone who smokes five joints per week may be taking in as many cancer-causing chemicals as someone who smokes a full pack of cigarettes every day.
- Lungs and airways
People who smoke marijuana often tend to develop the same kinds of breathing problems that cigarette smokers have. They suffer frequent coughing, phlegm production, and wheezing, and they tend to have more chest colds than non-users.
- Immune system
Animal studies have found that THC can damage the cells and tissues that help protect people from disease.
- Reproductive system
Heavy use of marijuana can affect both male and female hormones. Young men could have delayed puberty because of THC effects. Young women may find the drug disturbs their monthly cycle (ovulation and menstrual periods).
Q: Does marijuana lead to the use of other drugs?
A: Long-term studies of high school students and their patterns of drug use show that very few young people use other illegal drugs without first trying marijuana. Using marijuana puts children and teens in contact with people who are users and sellers of other drugs. So there is more of a risk that a marijuana user will be exposed to and urged to try more drugs. However, most marijuana users do not go on to use other illegal drugs.
Q: How can you tell if someone has been using marijuana?
A: If someone is high on marijuana, he or she might
- seem dizzy and have trouble walking;
- seem silly and giggly for no reason;
- have very red, bloodshot eyes; and
- have a hard time remembering things that just happened.
When the early effects fade, over a few hours, the user can become very sleepy.

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